Comparative Transcriptome Reconstruction of Four Hypericum Species Focused on Hypericin Biosynthesis

Comparative Transcriptome Reconstruction of Four Hypericum Species Focused on Hypericin Biosynthesis

Next generation sequencing technology rapidly developed research applications in the field of plant functional genomics. Several Hypericum spp. with an aim to generate and enhance gene annotations especially for genes coding the enzymes supposedly included in biosynthesis of valuable bioactive compounds were analyzed. The first de novo transcriptome profiling of Hypericum annulatum Moris, H. to...

Hypericin and pseudohypericin in some Hypericum species.

Hypericin and pseudohypericin were found in 27 of the 36 evaluated species from Hypericum L., belonging to 17 sections of the genus. Pseudohypericin is reported by us in 15 taxa for the first time. Most of the species contained both components and the amount of pseudohypericin usually exceeded that of hypericin. In H. hirsutum and H. empetrifolium only hypericin was found, whereas H. formosissi...

Comparative Transcriptome Analysis of Four Prymnesiophyte Algae

Genomic studies of bacteria, archaea and viruses have provided insights into the microbial world by unveiling potential functional capabilities and molecular pathways. However, the rate of discovery has been slower among microbial eukaryotes, whose genomes are larger and more complex. Transcriptomic approaches provide a cost-effective alternative for examining genetic potential and physiologica...

Effect of time of harvest on hypericin and essential oil content of hypericum performatum L.

Comparative transcriptome analysis of non-model Taxus species for taxol biosynthesis

Taxol is a known drug, approved by the food and drug administration in 1992 for the treatment of a wide range of cancers. Taxol is obtained from the taxus plant. Taxus plant has a very long life cycle and the production of taxol from the plant is a tedious process. In this study, we have tried to find new species of taxus which can be able to produce taxol and can overcome the burden of Taxus b...